Paediatric Cushing’s disease

Publicatiedatum: Zomer 2022

Cushing’s syndrome in childhood differs in a number of ways from the condition seen in adult patients, as Constantine Stratakis describes.

By far the most common type of Cushings syndrome has an exogenous cause, such as medication. l Endogenous causes are rare; they are all associated with a tumour of one form or another. For pre-pubertal children, and certainly for toddlers, the adrenals are more commonly the cause of endogenous Cushings syndrome, whereas pituitary tumours are more often to blame in older children. Ectopic sources of Cushings syndrome (a site other than the pituitary or adrenal) are extremely rare in children.

Source: ESPS